SPATA31E1 antibody (AA 331-430) (HRP)

Catalog No. ABIN1710970

Product Details anti-SPATA31E1 Antibody (HRP)

Target: SPATA31E1 (SPATA31 Subfamily E, Member 1 (SPATA31E1))

Binding Specificity: AA 331-430

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA31E1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf79

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SPATA31E1

Target: SPATA31E1 (SPATA31 Subfamily E, Member 1 (SPATA31E1))

Alternative Name: C9orf79 (SPATA31E1 Products)

Synonyms: C9orf79 antibody, FAM75E1 antibody, SPATA31 subfamily E member 1 antibody, SPATA31E1 antibody

Background:

Synonyms: C9orf79, Chromosome 9 open reading frame 79, S31E1_HUMAN, FAM75-like protein C9orf79.

Background: C9orf79 is a 1,445 amino acid single-pass membrane protein that belongs to the FAM75 family. The gene encoding C9orf79 maps to human chromosome 9, which consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 286234