C6ORF58 antibody (AA 251-330) (HRP)

Catalog No. ABIN1710944

Product Details anti-C6ORF58 Antibody (HRP)

Target: C6ORF58 (Chromosome 6 Open Reading Frame 58 (C6ORF58))

Binding Specificity: AA 251-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6ORF58 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf58

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C6ORF58

Target: C6ORF58 (Chromosome 6 Open Reading Frame 58 (C6ORF58))

Alternative Name: C6orf58 (C6ORF58 Products)

Synonyms: chromosome 6 open reading frame 58 antibody, liver-enriched gene 1, tandem duplicate 2 antibody, C6orf58 antibody, leg1.2 antibody

Background:

Synonyms: C6orf58, CF058_HUMAN, Chromosome 6 open reading frame 58, UPF0762 protein C6orf58.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf58 gene product has been provisionally designated C6orf58 pending further characterization.

Gene ID: 352999