GFM2 antibody (AA 151-250) (FITC)

Catalog No. ABIN1710501

Product Details anti-GFM2 Antibody (FITC)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Binding Specificity: AA 151-250

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFM2 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GFM2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: GFM2 (GFM2 Products)

Synonyms: RGD1309854 antibody, 6530419G12Rik antibody, A930009M04Rik antibody, EF-G2mt antibody, EFG2 antibody, MST027 antibody, RRF2mt antibody, mEF-G 2 antibody, si:dkey-35i22.3 antibody, zgc:153835 antibody, MRRF2 antibody, RRF2 antibody, hEFG2 antibody, ST15 antibody, G elongation factor, mitochondrial 2 antibody, G elongation factor mitochondrial 2 antibody, ribosome-releasing factor 2, mitochondrial antibody, reversion inducing cysteine rich protein with kazal motifs antibody, Gfm2 antibody, GFM2 antibody, gfm2 antibody, LOC662021 antibody, RECK antibody

Background:

Synonyms: EF-G2mt, EFG2, EFG2mt, elongation factor G 2, mitochondrial, Elongation factor G2, G elongation factor mitochondrial 2, GFM2, hEFG2, mEFG 2, mEFG2, Mitochondrial elongation factor G2, mitochondrial ribosome recycling factor 2, MRRF2, MST027, MSTP027, OTTHUMP00000222951, OTTHUMP00000222952, ribosome-releasing factor 2, mitochondrial, RRF2, RRF2mt.

Background: GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.

Gene ID: 84340

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization