Cyclin M3 antibody (AA 251-350) (Cy7)

Catalog No. ABIN1708321

Product Details anti-Cyclin M3 Antibody (Cy7)

Target: Cyclin M3 (CNNM3)

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin M3 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin M3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin M3

Target: Cyclin M3 (CNNM3)

Alternative Name: Cyclin M3 (CNNM3 Products)

Synonyms: ACDP3 antibody, Acdp3 antibody, Clp3 antibody, mACDP3 antibody, cyclin and CBS domain divalent metal cation transport mediator 3 antibody, cyclin M3 antibody, CNNM3 antibody, Cnnm3 antibody

Background:

Synonyms: ACDP3, Ancient conserved domain containing protein 3, CNNM3, DKFZp434I1016, FLJ20018, Metal transporter CNNM3, CNNM3_HUMAN.

Background: Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.

Gene ID: 26505