GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) antibody (Cy7)

Catalog No. ABIN1708083

Product Details

Target: GC-Rich Promoter Binding Protein 1 (GPBP1)

Binding Specificity: AA 11-110

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPBP1/Vasculin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: GC-Rich Promoter Binding Protein 1 (GPBP1)

Alternative Name: GPBP1/Vasculin (GPBP1 Products)

Synonyms: MGC80437 antibody, Vasculin antibody, DKFZp459A203 antibody, GPBP antibody, SSH6 antibody, VASCULIN antibody, 1700034P14Rik antibody, AU019836 antibody, D230035M11Rik antibody, Gpbp antibody, mGPBP antibody, RGD1305492 antibody, GC-rich promoter binding protein 1 L homeolog antibody, GC-rich promoter binding protein 1 antibody, gpbp1.L antibody, gpbp1 antibody, GPBP1 antibody, Gpbp1 antibody

Background:

Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

Gene ID: 65056