C9ORF139 antibody (AA 101-190) (Cy7)

Catalog No. ABIN1707337

Product Details anti-C9ORF139 Antibody (Cy7)

Target: C9ORF139 (Chromosome 9 Open Reading Frame 139 (C9ORF139))

Binding Specificity: AA 101-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9ORF139 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf139

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C9ORF139

Target: C9ORF139 (Chromosome 9 Open Reading Frame 139 (C9ORF139))

Alternative Name: C9orf139 (C9ORF139 Products)

Synonyms: chromosome 9 open reading frame 139 antibody, C9orf139 antibody

Background:

Synonyms: C9orf139, Chromosome 9 open reading frame 139, CI139_HUMAN, Uncharacterized protein C9orf139.

Background: C9orf139 (chromosome 9 open reading frame 139) is a 190 amino acid protein encoded by a gene that maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 401563