GEMIN6 antibody (AA 21-120) (Cy5)
-
- Target See all GEMIN6 Antibodies
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
-
Binding Specificity
- AA 21-120
-
Reactivity
- Human, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GEMIN6 antibody is conjugated to Cy5
-
Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Gemin 6
- Isotype
- IgG
- Top Product
- Discover our top product GEMIN6 Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
- Alternative Name
- Gemin 6 (GEMIN6 Products)
- Synonyms
- 2610019B15Rik antibody, 2810470M17Rik antibody, gemin6 antibody, gem nuclear organelle associated protein 6 antibody, gem (nuclear organelle) associated protein 6 antibody, gem nuclear organelle associated protein 6 S homeolog antibody, GEMIN6 antibody, Gemin6 antibody, gemin6.S antibody
- Background
-
Synonyms: FLJ23459, Gemin6, Gemin-6, Gem nuclear organelle associated protein 6, Gem-associated protein 6, GEMI6, GEMI6_HUMAN, Gemin-6, GEMIN6, SIP2.
Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
- Gene ID
- 79833
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-