POLM antibody (AA 261-360) (Cy5)
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- Target See all POLM Antibodies
- POLM (Polymerase (DNA Directed), mu (POLM))
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Binding Specificity
- AA 261-360
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLM antibody is conjugated to Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DNA polymerase mu
- Isotype
- IgG
- Top Product
- Discover our top product POLM Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- POLM (Polymerase (DNA Directed), mu (POLM))
- Alternative Name
- DNA polymerase mu (POLM Products)
- Synonyms
- polmu antibody, zgc:56122 antibody, POLM antibody, Pol Mu antibody, Tdt-N antibody, AI462166 antibody, B230309I03Rik antibody, polymerase (DNA directed), mu antibody, DNA polymerase mu antibody, polm antibody, POLM antibody, CC1G_09351 antibody, VDBG_09335 antibody, Polm antibody
- Background
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Synonyms: DNA Polymerase Mu, DNA-directed DNA polymerase mu, DNA-directed DNA/RNA polymerase mu, DPOLM_HUMAN, FLJ35482, Pol iota, Pol Mu, Polm, POLM protein, Polymerase DNA directed mu, Polymerase DNA directed mu, Tdt N, Tdt-N, TdtN, Terminal transferase.
Background: DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.
- Gene ID
- 27434
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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