IBA57 antibody (AA 131-230) (Cy3)

Catalog No. ABIN1703252

Product Details anti-IBA57 Antibody (Cy3)

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Binding Specificity: AA 131-230

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IBA57 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf69

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IBA57

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Alternative Name: C1orf69 (IBA57 Products)

Synonyms: C1orf69 antibody, 4930543L23Rik antibody, A230051G13Rik antibody, zgc:153540 antibody, IBA57 homolog, iron-sulfur cluster assembly antibody, IBA57 antibody, Iba57 antibody, iba57 antibody

Background:

Synonyms: C1orf69, CA069_HUMAN, CAF17_HUMAN, FLJ12734, FLJ13849, IBA57, IBA57 iron sulfur cluster assembly homolog, IBA57 iron sulfur cluster assembly homolog S. cerevisiae, Iron sulfur cluster assembly factor for biotin synthase and aconitase like, Iron-sulfur cluster assembly factor homolog, mitochondrial, Mitochondrial proteins with a mass of 57 kDa, Putative transferase C1orf69, Putative transferase C1orf69 mitochondrial, Putative transferase CAF17, mitochondrial.

Background: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Gene ID: 200205