GS28 antibody (AA 151-250) (Cy3)

Catalog No. ABIN1702133

Product Details anti-GS28 Antibody (Cy3)

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Binding Specificity: AA 151-250

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GS28 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GOSR1/GS28

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GS28

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Alternative Name: GOSR1/GS28 (GOSR1 Products)

Synonyms: CG7700 antibody, Dmel\\CG7700 antibody, FSG28 antibody, GOS28 antibody, dgos28 antibody, GOSR1 antibody, gosr1 antibody, zgc:112064 antibody, GOLIM2 antibody, GOS-28 antibody, GOS28/P28 antibody, GS28 antibody, P28 antibody, AI414660 antibody, AI426320 antibody, BB145494 antibody, GOSRI antibody, p28 antibody, Gos28 antibody, v-SNARE antibody, Golgi SNARE, 28 kDa antibody, golgi SNAP receptor complex member 1 antibody, Golgi SNAP receptor complex member 1 antibody, Gos28 antibody, GOSR1 antibody, gosr1 antibody, CpipJ_CPIJ014329 antibody, PAAG_02888 antibody, Tsp_07481 antibody, Gosr1 antibody, gos-28 antibody

Background:

Synonyms: P28, GS28, GOS28, GOLIM2, GOS-28, GOS28/P28, Golgi SNAP receptor complex member 1, 28 kDa Golgi SNARE protein, 28 kDa cis-Golgi SNARE p28, GOSR1

Background: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.

Gene ID: 9527

UniProt: O95249