GEN1 antibody (AA 51-150) (Biotin)

Catalog No. ABIN1701517

Product Details anti-GEN1 Antibody (Biotin)

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEN1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GEN1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GEN1

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Alternative Name: GEN1 (GEN1 Products)

Synonyms: 5830483C08Rik antibody, Gen antibody, RGD1559792 antibody, GEN1, Holliday junction 5' flap endonuclease antibody, GEN1 Holliday junction 5' flap endonuclease antibody, GEN1 antibody, Gen1 antibody

Background:

Synonyms: DKFZp781F0986, Flap endonuclease GEN homolog 1, FLJ40869, GEN 1, Gen, Gen homolog 1 endonuclease Drosophila, Gen homolog 1 endonuclease, GEN_HUMAN, GEN1.

Background: Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded.

Pathways: DNA Damage Repair