FAU antibody (AA 11-74) (Biotin)

Catalog No. ABIN1701502

Product Details anti-FAU Antibody (Biotin)

Target: FAU (Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously Expressed (FAU))

Binding Specificity: AA 11-74

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAU antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAU

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAU

Target: FAU (Finkel-Biskis-Reilly Murine Sarcoma Virus (FBR-MuSV) Ubiquitously Expressed (FAU))

Alternative Name: FAU/MNSF-beta (FAU Products)

Synonyms: FAU1 antibody, Fub1 antibody, Fubi antibody, MNSFbeta antibody, RPS30 antibody, S30 antibody, asr1 antibody, Asr1 antibody, MGC73171 antibody, zgc:73171 antibody, FAU, ubiquitin like and ribosomal protein S30 fusion antibody, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) antibody, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a antibody, FAU antibody, Fau antibody, faua antibody

Background:

Synonyms: 40S ribosomal protein S30, asr1, FAU, FAU encoded ubiquitin like protein, FAU1, FBR MuSV associated ubiquitously expressed, Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed fox derived, Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed, Finkel Biskis Reilly murine sarcoma virus ubiquitously expressed, FLJ22986, Fub1, Fubi, MNSFbeta, Monoclonal nonspecic suppressor factor beta, Ribosomal protein S30, RPS30, S30, UBIM_HUMAN, Ubiquitin like protein fubi and ribosomal protein S30, Ubiquitin like protein fubi, Ubiquitin like S30 fusion protein, Ubiquitin-like protein FUBI.

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36 % sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.

Gene ID: 2197

UniProt: P62861