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C1orf173 antibody (AA 301-400) (Biotin)

C1ORF173 Reactivity: Human, Mouse, Rat IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1701439
  • Target See all C1orf173 (C1ORF173) products
    C1orf173 (C1ORF173) (Chromosome 1 Open Reading Frame 173 (C1ORF173))
    Binding Specificity
    AA 301-400
    Reactivity
    Human, Mouse, Rat
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C1orf173 antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 2
    • 2
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf173
    Isotype
    IgG
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    C1orf173 (C1ORF173) (Chromosome 1 Open Reading Frame 173 (C1ORF173))
    Alternative Name
    C1orf173 (C1ORF173 Products)
    Synonyms
    RP11-653A5.1 antibody, glutamate rich 3 antibody, ERICH3 antibody
    Background

    Synonyms: C1orf173, Glutamate-rich protein 3, ERICH3

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf173 gene product has been provisionally designated C1orf173 pending further characterization. There are three isoforms of C1orf173 that are produced as a result of alternative splicing events.

    Gene ID
    127254
    UniProt
    Q5RHP9
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