Sorting Nexin 7 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1701372

Product Details anti-Sorting Nexin 7 Antibody (Biotin)

Target: Sorting Nexin 7 (SNX7)

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 7 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX7

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Sorting Nexin 7

Target: Sorting Nexin 7 (SNX7)

Alternative Name: SNX7 (SNX7 Products)

Synonyms: zgc:92458 antibody, SNX7 antibody, 2510028H01Rik antibody, sorting nexin 7 antibody, sorting nexin-7 antibody, SNX7 antibody, snx7 antibody, LOC715581 antibody, LOC716015 antibody, Snx7 antibody

Background:

Synonyms: MGC8717, DKFZP564F052, MGC8717, MGC8717, , Sorting nexin 7, Sorting nexin 7 isoform a, SNX7_HUMAN.

Background: Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX7 is unique in that it does not have a coiled coil region like some of the SNX family members. Mutations in the SNX7 gene have not been shown to cause any diseases.

Gene ID: 51375