NCKAP1L antibody (AA 1-100) (Biotin)

Catalog No. ABIN1701349

Product Details anti-NCKAP1L Antibody (Biotin)

Target: NCKAP1L (NCK-Associated Protein 1-Like (NCKAP1L))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKAP1L antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCKAP1L/HEM1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NCKAP1L

Target: NCKAP1L (NCK-Associated Protein 1-Like (NCKAP1L))

Alternative Name: NCKAP1L/HEM1 (NCKAP1L Products)

Synonyms: HEM1 antibody, 4930568P13Rik antibody, AI463083 antibody, Hem1 antibody, Hemp1 antibody, NCK associated protein 1 like antibody, zgc:172352 antibody, nck-associated protein 1-like antibody, NCK-associated protein 1-like antibody, NCKAP1L antibody, zgc:172352 antibody, LOC100030968 antibody, nckap1l antibody, LOC100618382 antibody, LOC100639088 antibody, Nckap1l antibody

Background:

Synonyms: 4930568P13Rik, AI463083, HEM1, Hematopoietic protein 1, HEMATOPOIETIC PROTEIN HEM-1, Hemp1, Membrane associated protein hem1, Membrane-associated protein HEM-1, NCK associated protein 1 like, Nck-associated protein 1-like, NCKAP1L, NCKPL_HUMAN.

Background: HEM1 is a 1,127 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the cell membrane. One of several members of the highly conserved HEM family of tissue-specific transmembrane proteins, HEM1 is expressed in cells of hematopoietic origin where it is thought to play an important role in oogenesis. The gene encoding HEM1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 3071

Pathways: Regulation of Actin Filament Polymerization