NAC1 antibody (AA 311-400) (Biotin)
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- Target See all NAC1 (NACC1) Antibodies
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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Binding Specificity
- AA 311-400
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NAC1 antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NAC1/BTBD14B
- Isotype
- IgG
- Top Product
- Discover our top product NACC1 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
- Alternative Name
- NAC1/BTBD14B (NACC1 Products)
- Synonyms
- BEND8 antibody, BTBD14B antibody, BTBD30 antibody, NAC-1 antibody, NAC1 antibody, NACC1 antibody, 2010001H03Rik antibody, 4930511N13Rik antibody, Btbd14b antibody, Nac1 antibody, Nac-1 antibody, nucleus accumbens associated 1 antibody, nucleus accumbens associated 1, BEN and BTB (POZ) domain containing antibody, NACC1 antibody, Nacc1 antibody
- Background
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Synonyms: BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, btbd14b, FLJ37383, NAC-1, NAC1, Nacc1, NACC1_HUMAN, Nucleus accumbens-associated protein 1.
Background: NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
- Gene ID
- 112939
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