GNPTAB antibody (AA 901-1000) (Biotin)

Catalog No. ABIN1701347

Product Details anti-GNPTAB Antibody (Biotin)

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Binding Specificity: AA 901-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPTAB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human N-acetylglucosamine-1-phosphotransferase subunit beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GNPTAB

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Alternative Name: GNPTAB (GNPTAB Products)

Synonyms: si:ch211-234f20.3 antibody, wu:fd55d09 antibody, zgc:122985 antibody, zgc:158502 antibody, GNPTA antibody, ICD antibody, EG432486 antibody, mKIAA1208 antibody, RGD1564821 antibody, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antibody, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antibody, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antibody, GNPTAB antibody, gnptab antibody, LOC100175423 antibody, Gnptab antibody

Background:

Synonyms: N-acetylglucosamine-1-phosphotransferase subunit beta, EC=2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, GNPTA, GNPTA_HUMAN, Gnptab, KIAA1208, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta.

Background: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

Gene ID: 79158