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EYA2 antibody (AA 201-300) (Biotin)

EYA2 Reactivity: Rat WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1701245
  • Target See all EYA2 Antibodies
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 42
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 53
    • 3
    Rabbit
    Clonality
    • 54
    • 2
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EYA2 antibody is conjugated to Biotin
    Application
    • 43
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EYA2
    Isotype
    IgG
    Top Product
    Discover our top product EYA2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Alternative Name
    EYA2 (EYA2 Products)
    Synonyms
    EYA2 antibody, zgc:92279 antibody, eab1 antibody, Eab1 antibody, EAB1 antibody, EYA transcriptional coactivator and phosphatase 2 antibody, EYA2 antibody, eya2 antibody, Eya2 antibody
    Background

    Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

    Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

    Gene ID
    2139
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