FBLN4 antibody (AA 331-443) (Biotin)

Catalog No. ABIN1701235

Product Details anti-FBLN4 Antibody (Biotin)

Target: FBLN4 (Fibulin 4 (FBLN4))

Binding Specificity: AA 331-443

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLN4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-FBLN4 antibody (Biotin) (ABIN1701235)

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Target Details for FBLN4

Target: FBLN4 (Fibulin 4 (FBLN4))

Alternative Name: EFEMP2/Fibulin 4 (FBLN4 Products)

Synonyms: CB257 antibody, fbln4 antibody, fc56c09 antibody, id:ibd2923 antibody, sb:cb257 antibody, wu:fc56c09.x1 antibody, ARCL1B antibody, FBLN4 antibody, MBP1 antibody, UPH1 antibody, 0610011K11Rik antibody, Fbln4 antibody, FIBL-4 antibody, Fibulin-4 antibody, H411 antibody, EGF-containing fibulin-like extracellular matrix protein 2 antibody, EGF containing fibulin-like extracellular matrix protein 2b antibody, fibulin 4 antibody, EGF containing fibulin like extracellular matrix protein 2 antibody, epidermal growth factor-containing fibulin-like extracellular matrix protein 2 antibody, Efemp2 antibody, efemp2b antibody, fbln4 antibody, EFEMP2 antibody

Background:

Synonyms: EFEMP2, EGF containing fibulin like extracellular matrix protein 2, EGF-containing fibulin-like extracellular matrix protein 2, FBLN 4, FBLN4, FBLN4_HUMAN, FIBL 4, FIBL-4, FIBL4, Fibulin4, Fibulin-4, MBP 1, MBP1, Mutant p53 binding protein 1, Protein UPH1, UPH 1, UPH1, UPH1 protein.

Background: Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-4, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family. Expressed ubiquitously with highest expression in heart, Fibulin-4 is essential for connective tissue development and elastic fiber formation, and may also play an important role in vascular patterning and collagen biosynthesis. Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body.

Gene ID: 30008