C8orf45 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1701200

Product Details anti-C8orf45 Antibody (Biotin)

Target: C8orf45 (Chromosome 8 Open Reading Frame 45 (C8orf45))

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8orf45 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C8orf45

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for C8orf45

Target: C8orf45 (Chromosome 8 Open Reading Frame 45 (C8orf45))

Alternative Name: C8orf45 (C8orf45 Products)

Synonyms: C8orf45 antibody, 6030422M02Rik antibody, minichromosome maintenance domain containing 2 antibody, MCMDC2 antibody, Mcmdc2 antibody

Background:

Synonyms: C8orf45, Chromosome 8 open reading frame 45, FLJ25692, Minichromosome maintenance complex component like, Uncharacterized protein C8orf45, MCMD2_HUMAN.

Background: Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf45 gene product has been provisionally designated C8orf45 pending further characterization.

Gene ID: 157777