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FFAR1 antibody (AA 121-220) (Biotin)

FFAR1 Reactivity: Human, Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1701125
  • Target See all FFAR1 Antibodies
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Binding Specificity
    • 14
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reactivity
    • 60
    • 30
    • 16
    • 5
    • 5
    • 3
    • 1
    Human, Mouse
    Host
    • 59
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    • 1
    Polyclonal
    Conjugate
    • 23
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FFAR1 antibody is conjugated to Biotin
    Application
    • 47
    • 20
    • 13
    • 13
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPR40
    Isotype
    IgG
    Top Product
    Discover our top product FFAR1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Alternative Name
    GPR40 (FFAR1 Products)
    Synonyms
    FFAR1 antibody, GPR40 antibody, FFA1R antibody, GPCR40 antibody, Gpr40 antibody, free fatty acid receptor 1 antibody, FFAR1 antibody, Ffar1 antibody
    Background

    Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Gene ID
    2864
    UniProt
    O14842
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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