Dymeclin antibody (AA 151-250) (Biotin)

Catalog No. ABIN1701022

Product Details anti-Dymeclin Antibody (Biotin)

Target: Dymeclin (DYM)

Binding Specificity: AA 151-250

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dymeclin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Dymeclin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Dymeclin

Target: Dymeclin (DYM)

Alternative Name: Dymeclin (DYM Products)

Synonyms: DYM antibody, LOC734107 antibody, dym antibody, DMC antibody, SMC antibody, 1810041M12Rik antibody, 4933427L07Rik antibody, C030019K18Rik antibody, RGD1309111 antibody, dymeclin antibody, dymeclin L homeolog antibody, DYM antibody, dym antibody, Dym antibody, dym.L antibody

Background:

Synonyms: DMC, Dyggve-Melchior-Clausen syndrome protein, DYM, FLJ20071, FLJ90130, SMC, DYM_HUMAN.

Background: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.

Gene ID: 54808