CRTAC1 antibody (AA 301-400) (Biotin)

Catalog No. ABIN1701011

Product Details anti-CRTAC1 Antibody (Biotin)

Target: CRTAC1 (Cartilage Acidic Protein 1 (CRTAC1))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAC1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTAC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CRTAC1

Target: CRTAC1 (Cartilage Acidic Protein 1 (CRTAC1))

Alternative Name: CRTAC1 (CRTAC1 Products)

Synonyms: ASPIP antibody, cb184 antibody, crtac1 antibody, sb:cb184 antibody, zgc:165343 antibody, aspic1 antibody, cep-68 antibody, MGC146658 antibody, ASPIC antibody, ASPIC1 antibody, CEP-68 antibody, 2810454P21Rik antibody, AW047536 antibody, Crtac1B antibody, Lotus antibody, W307 antibody, cartilage acidic protein 1 antibody, cartilage acidic protein 1a antibody, CRTAC1 antibody, crtac1a antibody, crtac1 antibody, aspip antibody, Crtac1 antibody

Background:

Synonyms: 68 kDa chondrocyte expressed protein, 68 kDa chondrocyte-expressed protein, Acidic secreted protein in cartilage, ASPIC, ASPIC1, Cartilage acidic protein 1, Cartilage acidic protein 1 precursor, CEP 68, CEP-68, CEP68, CRAC1_HUMAN, CRTAC1, Protein CRTAC1-B, W307.

Background: CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome.

Gene ID: 55118