STRA6 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1700978

Product Details anti-STRA6 Antibody (Biotin)

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA6 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STRA6

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Alternative Name: STRA6 (STRA6 Products)

Synonyms: MCOPCB8 antibody, MCOPS9 antibody, AI891933 antibody, RGD1307551 antibody, STRA6 antibody, im:7151282 antibody, wu:fc51h06 antibody, zgc:136689 antibody, mcops9 antibody, pp14296 antibody, stimulated by retinoic acid 6 antibody, stimulated by retinoic acid gene 6 antibody, stimulated by retinoic acid gene 6 homolog (mouse) antibody, STRA6 antibody, Stra6 antibody, stra6 antibody

Background:

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, STRA6_HUMAN.

Background: STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.

Gene ID: 64220

UniProt: Q9BX79

Pathways: Feeding Behaviour