GCM2 antibody (AA 61-160) (Biotin)

Catalog No. ABIN1700951

Product Details anti-GCM2 Antibody (Biotin)

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Binding Specificity: AA 61-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCM2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCM2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Alternative Name: GCM2 (GCM2 Products)

Synonyms: GCMb antibody, Gcm-2 antibody, gcm-2 antibody, GCMB antibody, hGCMb antibody, Gcm-rs1 antibody, Gcm1 antibody, Gcm1-rs2 antibody, glial cells missing homolog 2 antibody, glial cells missing homolog 2 (Drosophila) antibody, glial cells missing homolog 2 S homeolog antibody, GCM2 antibody, gcm2 antibody, gcm2.S antibody, Gcm2 antibody

Background:

Synonyms: Chorion-specic transcription factor GCMb, GCM mot protein 2, GCMb, Glial cells missing homolog 2, glial cells missing homolog b, GCM2_HUMAN.

Background: Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.

Gene ID: 9247

UniProt: O75603