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Manic Fringe antibody (AA 221-321) (Biotin)

MFNG Reactivity: Mouse ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700893
  • Target See all Manic Fringe (MFNG) Antibodies
    Manic Fringe (MFNG) (MFNG)
    Binding Specificity
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-321
    Reactivity
    • 28
    • 25
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 40
    • 4
    • 1
    Rabbit
    Clonality
    • 44
    • 1
    Polyclonal
    Conjugate
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Manic Fringe antibody is conjugated to Biotin
    Application
    • 20
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Cow,Sheep,Horse,Chimpanzee
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG
    Isotype
    IgG
    Top Product
    Discover our top product MFNG Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Manic Fringe (MFNG) (MFNG)
    Alternative Name
    Manic Fringe/MFNG (MFNG Products)
    Synonyms
    AW546563 antibody, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, MFNG antibody, Mfng antibody
    Background

    Synonyms: 3-N-acetylglucosaminyltransferase manic fringe, Beta-1, Beta-1,3-N-acetylglucosaminyltransferase manic fringe, MFNG, MFNG_HUMAN, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.

    Background: Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

    Gene ID
    4242
    Pathways
    Notch Signaling
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