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Thymopoietin antibody (AA 51-150) (Biotin)

TMPO Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700889
  • Target See all Thymopoietin (TMPO) Antibodies
    Thymopoietin (TMPO)
    Binding Specificity
    • 14
    • 13
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 63
    • 20
    • 15
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 5
    Rabbit
    Clonality
    • 59
    • 4
    Polyclonal
    Conjugate
    • 29
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Thymopoietin antibody is conjugated to Biotin
    Application
    • 56
    • 24
    • 19
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Cow
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LAP2
    Isotype
    IgG
    Top Product
    Discover our top product TMPO Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Thymopoietin (TMPO)
    Alternative Name
    LAP2 alpha (TMPO Products)
    Synonyms
    LAP2 antibody, CMD1T antibody, LEMD4 antibody, PRO0868 antibody, TP antibody, lap2 antibody, LAP2beta antibody, 5630400D24Rik antibody, AI195756 antibody, AI606875 antibody, AW214352 antibody, AW547477 antibody, tmpo antibody, wu:fc26f12 antibody, wu:fd21f02 antibody, wu:fi29h05 antibody, thymopoietin antibody, thymopoietin S homeolog antibody, thymopoietin a antibody, TMPO antibody, Tmpo antibody, tmpo.S antibody, tmpoa antibody
    Background

    Synonyms: Isoforms beta/gamma, Lamina associated polypeptide 2 alpha, Lamina associated polypeptide 2, LAP2, Thymopoietin, Thymopoietin isoform alpha, TMPO, TP alpha, TP, LAP2 alpha, LAP2A_HUMAN.

    Background: The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (, _,_, and ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2 and LAP2_ associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2_ also binds to lamin B. LAP2 is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.

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