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GEMIN7 antibody (AA 21-120) (Biotin)

GEMIN7 Reactivity: Human, Rat ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700552
  • Target See all GEMIN7 Antibodies
    GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
    Binding Specificity
    • 15
    • 9
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivity
    • 38
    • 16
    • 10
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 34
    • 4
    Rabbit
    Clonality
    • 35
    • 3
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GEMIN7 antibody is conjugated to Biotin
    Application
    • 14
    • 13
    • 13
    • 13
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Dog,Cow,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Gemin 7
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN7 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
    Alternative Name
    Gemin 7 (GEMIN7 Products)
    Synonyms
    SIP3 antibody, GEMIN7 antibody, Gemin7 antibody, 2400008I04Rik antibody, AI120175 antibody, AI461688 antibody, gem nuclear organelle associated protein 7 antibody, gem (nuclear organelle) associated protein 7 antibody, GEMIN7 antibody, Gemin7 antibody
    Background

    Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

    Background: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

    Gene ID
    79760
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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