Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RUSC1 antibody (AA 281-380) (Biotin)

RUSC1 Reactivity: Human, Mouse ELISA, WB, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700389
  • Target See all RUSC1 Antibodies
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Binding Specificity
    • 14
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 281-380
    Reactivity
    • 26
    • 18
    • 4
    Human, Mouse
    Host
    • 24
    • 2
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RUSC1 antibody is conjugated to Biotin
    Application
    • 20
    • 13
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RUSC1
    Isotype
    IgG
    Top Product
    Discover our top product RUSC1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Alternative Name
    RUSC1 (RUSC1 Products)
    Synonyms
    NESCA antibody, 2210403N08Rik antibody, AA408288 antibody, RUN and SH3 domain containing 1 antibody, RUSC1 antibody, Rusc1 antibody
    Background

    Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.

    Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.

You are here:
Support