ITPA antibody (AA 1-100) (Biotin)

Catalog No. ABIN1700347

Product Details anti-ITPA Antibody (Biotin)

Target: ITPA (Inosine Triphosphatase (ITPA))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPA antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Inosine triphosphate pyrophosphatase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Alternative Name: Inosine triphosphate pyrophosphatase (ITPA Products)

Synonyms: DDBDRAFT_0215619 antibody, DDBDRAFT_0238062 antibody, DDB_0215619 antibody, DDB_0238062 antibody, 2010016I08Rik antibody, AU020102 antibody, Itp antibody, C20orf37 antibody, HLC14-06-P antibody, dJ794I6.3 antibody, ITPase antibody, NTPase antibody, si:ch73-18j6.1 antibody, si:dkey-19f21.1 antibody, inosine triphosphatase antibody, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) antibody, Inosine triphosphate pyrophosphatase antibody, inosine triphosphatase S homeolog antibody, itpa antibody, ITPA antibody, LOC733043 antibody, Itpa antibody, pco148511 antibody, itpa.S antibody

Background:

Synonyms: ITPase, C20orf37, dJ794I6.3, HLC14-06-P, Inosine triphosphatase nucleoside triphosphate pyrophosphatase, Inosine triphosphatase, inosine triphosphatase-A, Inosine triphosphate pyrophosphatase, Inosine triphosphate pyrophosphohydrolase, Itpa, ITPA_HUMAN, ITPase, My049, My049 protein, Non canonical purine NTP pyrophosphatase, Non standard purine NTP pyrophosphatase, NTPase, nucleoside triphosphate diphosphatase, Nucleoside triphosphate pyrophosphatase, OK/SW-cl.9, OTTHUMP00000030094, OTTHUMP00000160459, Putative oncogene protein hlc14-06-p.

Background: ITPase (inosine triphosphate pyrophosphatase) is also known as putative oncogene protein hlc14-06-p or ITPA (inosine triphosphatase (nucleoside triphosphate pyrophosphatase)) and is a 194 amino acid protein. ITPase is abundantly expressed in heart, liver, sex glands, thyroid and adrenal gland, and is localized to the cytoplasm in the cell. ITPase catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPase can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPase result in ITPase deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

Gene ID: 3704