GMFG antibody (AA 51-142) (Biotin)

Catalog No. ABIN1700316

Product Details anti-GMFG Antibody (Biotin)

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Binding Specificity: AA 51-142

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMFG antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMFG/GMF-gamma

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GMFG

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Alternative Name: GMFG/GMF-gamma (GMFG Products)

Synonyms: GMF-GAMMA antibody, 0610039G16Rik antibody, 2310057N07Rik antibody, AI324845 antibody, gmf-gamma antibody, MGC108238 antibody, zgc:136987 antibody, glia maturation factor gamma antibody, glia maturation factor, gamma antibody, glia maturation factor, gamma S homeolog antibody, GMFG antibody, Gmfg antibody, gmfg.S antibody, gmfg antibody

Background:

Synonyms: Glia maturation factor gamma, Glia maturation factor, gamma, GMF GAMMA, GMF-gamma, Gmfg, GMFG_HUMAN, MGC126867.

Background: GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.

Gene ID: 9535