Ferredoxin Reductase antibody (AA 401-491) (Biotin)

Catalog No. ABIN1700281

Product Details anti-Ferredoxin Reductase Antibody (Biotin)

Target: Ferredoxin Reductase (FDXR)

Binding Specificity: AA 401-491

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ferredoxin Reductase antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ferredoxin Reductase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Ferredoxin Reductase

Target: Ferredoxin Reductase (FDXR)

Alternative Name: Ferredoxin Reductase/ADXR (FDXR Products)

Synonyms: AR antibody, AdR antibody, FDXR antibody, PSPTO4024 antibody, ADXR antibody, fdxr antibody, ferredoxin reductase antibody, ferredoxin--NADP reductase antibody, ferredoxin--NADP reductase Fpr antibody, ferredoxin reductase L homeolog antibody, FDXR antibody, Fdxr antibody, fnr-1 antibody, fpr antibody, SPO2637 antibody, fdxr.L antibody

Background:

Synonyms: adrenodoxin reductase, ADRO_HUMAN, ADXR, AR, FDXR, Ferredoxin NADP+ reductase, Ferredoxin reductase, Ferredoxin--NADP+ reductase, mitochondrial, NADPH adrenodoxin oxidoreductase mitochondrial, NADPH:adrenodoxin oxidoreductase.

Background: Adrenodoxin Reductase (ADX Reductase) is a mitochondrial flavoprotein that receives electrons from NADPH and thereby initiates the electron-transport chain serving mitochondrial cytochromes P450. ADX Reductase participates in cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-? hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney and sterol C-27 hydroxylation in the liver. Alternate splicing of ADX Reductase produces two isoforms. Human ADX Reductase maps to human chromosome 17q24-q25.

Gene ID: 2232