C9orf142 antibody (AA 51-150) (Biotin)
-
- Target See all C9orf142 (C9ORF142) products
- C9orf142 (C9ORF142) (Chromosome 9 Open Reading Frame 142 (C9ORF142))
-
Binding Specificity
- AA 51-150
-
Reactivity
- Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This C9orf142 antibody is conjugated to Biotin
-
Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C9orf142
- Isotype
- IgG
-
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- C9orf142 (C9ORF142) (Chromosome 9 Open Reading Frame 142 (C9ORF142))
- Alternative Name
- C9orf142 (C9ORF142 Products)
- Synonyms
- PAXX, non-homologous end joining factor antibody, PAXX antibody
- Background
-
Synonyms: C9orf142, Chromosome 9 open reading frame 142, CI142_HUMAN, Uncharacterized protein C9orf142.
Background: C9orf142 (chromosome 9 open reading frame 142) is a 204 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf142 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
- Gene ID
- 286257
-