Apolipoprotein L 4 antibody (AA 1-100) (Biotin)

Catalog No. ABIN1699863

Product Details anti-Apolipoprotein L 4 Antibody (Biotin)

Target: Apolipoprotein L 4 (APOL4) (Apolipoprotein L, 4 (APOL4))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein L 4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APOL4/Apolipoprotein L4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Apolipoprotein L 4

Target: Apolipoprotein L 4 (APOL4) (Apolipoprotein L, 4 (APOL4))

Alternative Name: APOL4/Apolipoprotein L4 (APOL4 Products)

Synonyms: APOL4 antibody, DKFZp469B1920 antibody, APOL-IV antibody, APOLIV antibody, apolipoprotein L, 4 antibody, apolipoprotein L4 antibody, APOL4 antibody

Background:

Synonyms: APOL IV, ApoL-IV, APOL4, APOL4_HUMAN, Apolipoprotein L IV, Apolipoprotein L-IV, Apolipoprotein L4, APOLIV, CTA 212A2.2, OTTHUMP00000028937.

Background: The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-IV (apolipoprotein L-IV), also known as APOL4, is a 351 amino acid protein that exists as multiple alternatively spliced isoforms, one of which is secreted. Expressed in spleen, placenta, spinal cord, uterus, testis and trachea, apoL-IV is thought to play a role in lipid exchange and transport throughout the body and may be involved in reverse cholesterol transport, specifically from peripheral cells to the liver. Overexpression of apoL-IV is associated with schizophrenia, suggesting that apoL-IV may play a role in the pathogenesis of neural disorders.

Gene ID: 80832