METTL24 antibody (AA 301-366) (AbBy Fluor® 647)

Catalog No. ABIN1699030

Product Details anti-METTL24 Antibody (AbBy Fluor® 647)

Target: METTL24 (Methyltransferase Like 24 (METTL24))

Binding Specificity: AA 301-366

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL24 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf186

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for METTL24

Target: METTL24 (Methyltransferase Like 24 (METTL24))

Alternative Name: C6orf186 (METTL24 Products)

Synonyms: C6orf186 antibody, dJ71D21.2 antibody, 9030224M15Rik antibody, methyltransferase like 24 antibody, METTL24 antibody, Mettl24 antibody

Background:

Synonyms: C6orf186, MET24_HUMAN, Chromosome 6 open reading frame 186, dJ71D21.2, UPF0624 protein C6orf186.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf186 gene product has been provisionally designated C6orf186 pending further characterization.

Gene ID: 728464