NCKAP5 antibody (AA 1-100) (AbBy Fluor® 647)

Catalog No. ABIN1698553

Product Details anti-NCKAP5 Antibody (AbBy Fluor® 647)

Target: NCKAP5 (NCK Associated Protein 5 (NCKAP5))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKAP5 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCKAP5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NCKAP5

Target: NCKAP5 (NCK Associated Protein 5 (NCKAP5))

Alternative Name: Nckap5 (NCKAP5 Products)

Synonyms: ERIH1 antibody, ERIH2 antibody, NAP5 antibody, 8430408F21 antibody, D130011D22Rik antibody, E030049G20Rik antibody, Erih1 antibody, Erih2 antibody, Gm1548 antibody, Nap5 antibody, RGD1564507 antibody, NCK associated protein 5 antibody, NCK-associated protein 5 antibody, NCKAP5 antibody, Nckap5 antibody

Background:

Synonyms: ERIH1, ERIH2, NAP-5, NAP5, Nck-associated protein 5, NCKAP5, NCKP5_HUMAN, Peripheral clock protein.

Background: NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is due to mutations in the ALMS1 gene.