MKLN1 antibody (AA 301-400) (AbBy Fluor® 647)
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- Target See all MKLN1 Antibodies
- MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))
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Binding Specificity
- AA 301-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MKLN1 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MKLN1
- Isotype
- IgG
- Top Product
- Discover our top product MKLN1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))
- Alternative Name
- MKLN1 (MKLN1 Products)
- Synonyms
- fc60a07 antibody, wu:fc60a07 antibody, mkln1 antibody, MGC81665 antibody, MKLN1 antibody, MGC139211 antibody, TWA2 antibody, A130067F06Rik antibody, AU015903 antibody, BB154892 antibody, Muskelin antibody, DKFZp468G1027 antibody, muskelin 1, intracellular mediator containing kelch motifs antibody, muskelin 1 antibody, muskelin 1 L homeolog antibody, mkln1 antibody, MKLN1 antibody, mkln1.L antibody, Mkln1 antibody
- Background
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Synonyms: MKLN 1, Mkln1, MKLN1_HUMAN, muskelin 1, intracellular mediator containing kelch mots, Muskelin.
Background: Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98 % amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively.
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