Folate Receptor 4 antibody (AbBy Fluor® 647)

Catalog No. ABIN1698474

Product Details anti-Folate Receptor 4 Antibody (AbBy Fluor® 647)

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Folate Receptor 4 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Folate Receptor 4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for Folate Receptor 4

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Alternative Name: Folate Receptor 4 (FOLR4 Products)

Synonyms: 0910001L11Rik antibody, C86255 antibody, Folbp3 antibody, IZUMO1 receptor, JUNO antibody, Izumo1r antibody, IZUMO1R antibody

Background:

Folate receptor 4 is a highly expressed cell surface marker of regulatory T cells. Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:FOLR4/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. This receptor does not bind folate.

Subcellular location: Cell membrane

Synonyms: Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, FOLR4, JUNO

Gene ID: 390243