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HESX Homeobox 1 antibody (AA 51-150) (AbBy Fluor® 647)

HESX1 Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN1698217
  • Target See all HESX Homeobox 1 (HESX1) Antibodies
    HESX Homeobox 1 (HESX1)
    Binding Specificity
    • 14
    • 7
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 16
    • 13
    • 4
    Rat
    Host
    • 23
    • 4
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HESX Homeobox 1 antibody is conjugated to AbBy Fluor® 647
    Application
    • 12
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HESX1
    Isotype
    IgG
    Top Product
    Discover our top product HESX1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HESX Homeobox 1 (HESX1)
    Alternative Name
    HESX1 (HESX1 Products)
    Synonyms
    HES-1 antibody, Rpx antibody, RGD1563858 antibody, ANF antibody, CPHD5 antibody, RPX antibody, XANF-2 antibody, Xanf antibody, Xanf-1 antibody, Xanf1 antibody, Xanf2 antibody, anf2 antibody, anf2-A antibody, rpx antibody, anf1 antibody, hesx1 antibody, xanf-1 antibody, HESX1 antibody, GANF antibody, Anf antibody, danf antibody, zanf antibody, homeobox gene expressed in ES cells antibody, HESX homeobox 1 antibody, HESX homeobox 1 S homeolog antibody, HESX homeobox 1 L homeolog antibody, Hesx1 antibody, HESX1 antibody, hesx1.S antibody, hesx1.L antibody, hesx1 antibody
    Background

    Synonyms: NULL

    Background: The homeobox protein, HESX1, which is also known as Rathke?s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.

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