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Supervillin antibody (AA 51-150) (AbBy Fluor® 555)

SVIL Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN1697109
  • Target See all Supervillin (SVIL) Antibodies
    Supervillin (SVIL)
    Binding Specificity
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 51-150
    Reactivity
    • 16
    • 15
    Mouse
    Host
    • 24
    • 5
    • 1
    Rabbit
    Clonality
    • 26
    • 4
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Supervillin antibody is conjugated to AbBy Fluor® 555
    Application
    • 30
    • 12
    • 12
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Supervillin
    Isotype
    IgG
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  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Supervillin (SVIL)
    Alternative Name
    Supervillin (SVIL Products)
    Synonyms
    sb:cb867 antibody, svil antibody, wu:fd05a09 antibody, SVIL antibody, DKFZp468F0819 antibody, AU024053 antibody, B430302E16Rik antibody, supervillin a antibody, supervillin antibody, supervillin, putative antibody, svila antibody, SVIL antibody, LOC5577073 antibody, CpipJ_CPIJ003700 antibody, Smp_148580 antibody, svil antibody, Svil antibody
    Background

    Synonyms: Supervillin, Archvillin, p205/p250, SVIL

    Background: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

    Gene ID
    6840
    UniProt
    O95425
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