SCUBE3 antibody (AA 451-550) (AbBy Fluor® 488)
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- Target See all SCUBE3 Antibodies
- SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
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Binding Specificity
- AA 451-550
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCUBE3 antibody is conjugated to AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SCUBE3
- Isotype
- IgG
- Top Product
- Discover our top product SCUBE3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
- Alternative Name
- SCUBE3 (SCUBE3 Products)
- Synonyms
- CEGF3 antibody, D030038I21Rik antibody, signal peptide, CUB domain and EGF like domain containing 3 antibody, signal peptide, CUB domain, EGF-like 3 antibody, signal peptide, CUB and EGF-like domain-containing protein 3 antibody, SCUBE3 antibody, scube3 antibody, Scube3 antibody, LOC100152993 antibody
- Background
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Synonyms: CEGF3, CUB and EGF containing protein 3, CUB and EGF-like domain-containing protein 3, CUB domain and EGF like repeat containing 3, DKFZp686B09105, DKFZp686B1223, DKFZp686D20108, FLJ34743, OTTHUMP00000016250, SCUB3_HUMAN, SCUBE 3, SCUBE3, Signal peptide, Signal peptide CUB and EGF like domain containing protein 3, Signal peptide CUB domain EGF like 3.
Background: SCUBE3 is a novel secreted 993 amino acid cell-surface osteoblast protein that plays an important role in bone cell biology. While highly expressed in osteoblasts, SCUBE3 expression is unobservable or very low in non-bone tissues. SCUBE3 forms homo-oligomers and hetero-oligomers with SCUBE1, and may undergo C-terminal proteolytic cleavage or become N-glycosylated following translation. Two SCUBE3 isoforms exist as a result of alternative splicing events. SCUBE3 contains one CUB domain and nine EGF-like domains, and is encoded by a gene which maps to human chromosome 6p21.31, a region associated with a rare form of metabolic bone disease known as Paget's disease. Chromosome 6 contains 170 million base pairs and comprises nearly 6 % of the human genome.
- Gene ID
- 222663
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