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PHC1 antibody (AA 751-900) (AbBy Fluor® 488)

PHC1 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1695789
  • Target See all PHC1 Antibodies
    PHC1 (Polyhomeotic-Like 1 (PHC1))
    Binding Specificity
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 751-900
    Reactivity
    • 40
    • 11
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 35
    • 5
    Rabbit
    Clonality
    • 37
    • 3
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHC1 antibody is conjugated to AbBy Fluor® 488
    Application
    • 12
    • 12
    • 11
    • 9
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EDR1/PHC1
    Isotype
    IgG
    Top Product
    Discover our top product PHC1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PHC1 (Polyhomeotic-Like 1 (PHC1))
    Alternative Name
    EDR1/PHC1 (PHC1 Products)
    Synonyms
    EDR1 antibody, HPH1 antibody, RAE28 antibody, AW557034 antibody, Edr antibody, Edr1 antibody, Mph1 antibody, Rae-28 antibody, rae28 antibody, polyhomeotic homolog 1 antibody, polyhomeotic-like 1 (Drosophila) antibody, Phc1 antibody, PHC1 antibody
    Background

    Synonyms: Early development regulatory protein 1, EDR1 PH1, hPH1, mPH1, PH1, Polyhomeotic-like protein 1, Rae28, PHC1_HUMAN.

    Background: PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

    Gene ID
    1911
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