FPGT antibody (AA 251-350) (AbBy Fluor® 488)

Catalog No. ABIN1695497

Product Details anti-FPGT Antibody (AbBy Fluor® 488)

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGT antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FPGT

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FPGT

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Alternative Name: FPGT (FPGT Products)

Synonyms: DDBDRAFT_0186414 antibody, DDBDRAFT_0233144 antibody, DDB_0186414 antibody, DDB_0233144 antibody, FPGT antibody, DKFZp459M111 antibody, fpgt antibody, zgc:110694 antibody, GFPP antibody, 1700016E03Rik antibody, fucose-1-phosphate guanylyltransferase antibody, fucose-1-phosphate guanylyltransferase L homeolog antibody, fpgt antibody, FPGT antibody, fpgt.L antibody, Fpgt antibody

Background:

Synonyms: FPGT, FPGT_HUMAN, Fucose 1 phosphate guanyltransferase, Fucose 1 phosphate guanylyltransferase, Fucose-1-phosphate guanylyltransferase, GDP beta L fucose pyrophosphorylase, GDP L fucose diphosphorylase, GDP L fucose pyrophosphorylase, GDP-L-fucose diphosphorylase, GDP-L-fucose pyrophosphorylase, GFPP.

Background: Guanylyltransferase enzymes transfer one molecule of GTP to another molecule and also function in the transfer of guanosine nucleotides to sugar molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. L-fucose is an important sugar in complex carbohydrates that is frequently found on plant and mammalian N-linked glycans. FPGT (Fucose-1-phosphate guanylyltransferase), also known as GFPP (GDP-L-fucose pyrophosphorylase), is a 594 amino acid cytoplasmic protein that catalyzes the formation of GDP-L-fucose from L-fucose-1-phosphate and GTP. FPGT functions to reutilize the L-fucose that is produced uopn glycoprotein and glycolipid turnover.

Gene ID: 8790