FIP1L1 antibody (AA 501-594) (AbBy Fluor® 488)
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- Target See all FIP1L1 Antibodies
- FIP1L1 (FIP1 Like 1 (FIP1L1))
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Binding Specificity
- AA 501-594
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FIP1L1 antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FIP1L1
- Isotype
- IgG
- Top Product
- Discover our top product FIP1L1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FIP1L1 (FIP1 Like 1 (FIP1L1))
- Alternative Name
- FIP1L1 (FIP1L1 Products)
- Synonyms
- FIP1 antibody, Rhe antibody, hFip1 antibody, 1300019H17Rik antibody, Rje antibody, fip1l1 antibody, wu:fd36f11 antibody, zgc:103421 antibody, factor interacting with PAPOLA and CPSF1 antibody, factor interacting with PAPOLA and CPSF1 S homeolog antibody, FIP1 like 1 (S. cerevisiae) antibody, FIP1 like 1b (S. cerevisiae) antibody, fip1l1 antibody, FIP1L1 antibody, fip1l1.S antibody, Fip1l1 antibody, fip1l1b antibody
- Background
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Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.
Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.
- Gene ID
- 81608
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