IFT122 antibody (AA 1-100) (AbBy Fluor® 488)

Catalog No. ABIN1695110

Product Details anti-IFT122 Antibody (AbBy Fluor® 488)

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT122 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFT122

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IFT122

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Alternative Name: Ift122 (IFT122 Products)

Synonyms: C86139 antibody, Wdr10 antibody, sopb antibody, CED antibody, CED1 antibody, SPG antibody, WDR10 antibody, WDR10p antibody, WDR140 antibody, intraflagellar transport 122 antibody, intraflagellar transport protein 122 homolog antibody, IFT122 antibody, ift122 antibody, LOC100639275 antibody, LOC100649523 antibody, Ift122 antibody

Background:

Synonyms: CED, 122_HUMAN, T122, Intraflagellar transport 122 homolog Chlamydomonas, Intraflagellar transport protein 122 homolog, SPG, WD repeat domain 10, WD repeat-containing protein 10, WD repeat-containing protein 140, WDR10, WDR10p, WDR140.

Background: IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathways: Tube Formation, Embryonic Body Morphogenesis