FAM20C antibody (AA 351-450) (AbBy Fluor® 488)
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- Target See all FAM20C Antibodies
- FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
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Binding Specificity
- AA 351-450
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAM20C antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Monkey
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FAM20C
- Isotype
- IgG
- Top Product
- Discover our top product FAM20C Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
- Alternative Name
- FAM20C (FAM20C Products)
- Synonyms
- DMP-4 antibody, DMP4 antibody, GEF-CK antibody, RNS antibody, C76981 antibody, mKIAA4081 antibody, RGD1311980 antibody, si:ch73-266a4.1 antibody, FAM20C, golgi associated secretory pathway kinase antibody, family with sequence similarity 20, member C antibody, family with sequence similarity 20, member Cb antibody, FAM20C antibody, Fam20c antibody, fam20cb antibody
- Background
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Synonyms: C76981, Dentin matrix protein 4, DKFZp547C074, DMP-4, DMP4, DMP4_HUMAN, Extracellular serine/threonine protein kinase Fam20C, Fam20C, Family with sequence similarity 20 member C, GEF CK, Golgi enriched fraction casein kinase, Protein FAM20C, RNS antibod.
Background: The FAM20 proteins are a family of secreted proteins that regulate differentiation and function of hematopoietic and other tissues. FAM20C, also known as DMP4 (Dentin matrix protein 4), is a 570 amino acid secreted protein that binds calcium and may play a role in dentin mineralization. Defects in the gene encoding FAM20C are the cause of Raine syndrome (Lethal osteosclerotic bone dysplasia), an autosomal recessive osteosclerotic bone dysplasia, that is characterized by generalized osteosclerosis, microencephaly and craniofacial dysplasia. Usually, affected individuals survive only days or weeks. The mutations of the FAM20C gene include four nonsynomous base changes and four splice-site changes that have a detrimental affect on splicing.
- Gene ID
- 56975
- UniProt
- Q8IXL6
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