MAEA antibody (AA 171-250) (AbBy Fluor® 488)

Catalog No. ABIN1695071

Product Details anti-MAEA Antibody (AbBy Fluor® 488)

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Binding Specificity: AA 171-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEA antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EMP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAEA

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Alternative Name: MAEA/EMP/HLC10 (MAEA Products)

Synonyms: emp antibody, emlp antibody, pig5 antibody, hlc-10 antibody, MGC81431 antibody, MAEA antibody, MGC64455 antibody, MGC89777 antibody, EMLP antibody, EMP antibody, GID9 antibody, HLC-10 antibody, PIG5 antibody, 1110030D19Rik antibody, Gid9 antibody, wu:fb20a09 antibody, zgc:63708 antibody, macrophage erythroblast attacher S homeolog antibody, macrophage erythroblast attacher antibody, macrophage erythroblast attacher L homeolog antibody, maea.S antibody, MAEA antibody, maea antibody, Maea antibody, maea.L antibody

Background:

Synonyms: 1110030D19Rik, Cell proliferation inducing gene 5 protein, Cell proliferation-inducing gene 5 protein, EMP, Erythroblast macrophage protein, HLC 10, HLC-10, HLC10, Human lung cancer oncogene 10 protein, Lung cancer related protein 10, lung cancer-related protein 10, Macrophage erythroblast attacher, MAEA, MAEA_HUMAN, MGC93683, PIG5, proliferation-inducing gene 5.

Background: Emp is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, Emp contains one CTLH domain and one LisH domain. Emp can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, Emp is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Although the exact function of Emp is unknown, Emp is suggested to be involvement in erythroblast-macrophage cell attachment, terminal maturation and enucleation of erythroid cells, and inhibiting apoptosis of erythroblasts.

Gene ID: 10296