NUP210 antibody (AA 1161-1260) (AbBy Fluor® 488)

Catalog No. ABIN1694870

Product Details anti-NUP210 Antibody (AbBy Fluor® 488)

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Binding Specificity: AA 1161-1260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP210 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GP210

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NUP210

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Alternative Name: GP210 (NUP210 Products)

Synonyms: 9830001L10 antibody, AI836801 antibody, Pom210 antibody, gp190 antibody, gp210 antibody, GP210 antibody, POM210 antibody, nucleoporin 210 antibody, nucleoporin 210kDa L homeolog antibody, NUP210 antibody, Nup210 antibody, nup210.L antibody

Background:

Synonyms: FLJ22389, GP 210, KIAA0906, Nuclear envelope pore membrane protein POM 210, Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nucleoporin 210, Nucleoporin 210 kDa, Nucleoporin Nup210, Nucleoporin210, NUP 210, NUP210, PO210_HUMAN, POM 210, POM210, Pore membrane protein of 210 kDa.

Background: The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). gp210, also known as Nup210 (nucleoporin 210 kDa) or POM210, is a 1,887 amino acid single-pass type I membrane protein that localizes to both the endoplasmic reticulum and to the nucleus, specifically within the NPC. Expressed ubiquitously with highest expression in pancreas, testis, lung, ovary and liver, gp210 functions as a nucleoporin that is capable of dimerization and is essential for the assembly, fusion and structural integrity of the NPC. gp210 exists as multiple alternatively spliced isoforms and is subject to post-translational phosphorylation.

Gene ID: 23225

UniProt: Q8TEM1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection