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Acetyl-CoA Carboxylase beta antibody (pSer220) (AbBy Fluor® 488)

ACACB Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1694640
  • Target See all Acetyl-CoA Carboxylase beta (ACACB) Antibodies
    Acetyl-CoA Carboxylase beta (ACACB)
    Binding Specificity
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    pSer220
    Reactivity
    • 27
    • 8
    • 1
    Human
    Host
    • 24
    • 3
    • 1
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Acetyl-CoA Carboxylase beta antibody is conjugated to AbBy Fluor® 488
    Application
    • 12
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220
    Isotype
    IgG
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    Discover our top product ACACB Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Acetyl-CoA Carboxylase beta (ACACB)
    Alternative Name
    Acetyl Coenzyme A Carboxylase beta (ACACB Products)
    Synonyms
    F15C21.2 antibody, F15C21_2 antibody, acetyl-CoA carboxylase 2 antibody, ACC2 antibody, ACCB antibody, HACC275 antibody, Acc2 antibody, AI597064 antibody, AW743042 antibody, Accb antibody, acetyl-CoA carboxylase 2 antibody, acetyl-CoA carboxylase beta antibody, acetyl-Coenzyme A carboxylase beta antibody, ACC2 antibody, ACACB antibody, Acacb antibody
    Background

    Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220, ACACB_HUMAN

    Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

    UniProt
    O00763
    Pathways
    AMPK Signaling, Ribonucleoside Biosynthetic Process
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