TEX35 antibody (AA 101-200) (AbBy Fluor® 488)

Catalog No. ABIN1694431

Product Details anti-TEX35 Antibody (AbBy Fluor® 488)

Target: TEX35 (Testis Expressed 35 (TEX35))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEX35 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf49

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TEX35

Target: TEX35 (Testis Expressed 35 (TEX35))

Alternative Name: C1orf49 (TEX35 Products)

Synonyms: C1orf49 antibody, TSC24 antibody, 1700057K13Rik antibody, C16H1orf49 antibody, testis expressed 35 antibody, TEX35 antibody, Tex35 antibody

Background:

Synonyms: C1orf49, CA049_HUMAN, Chromosome 1 open reading frame 49, RP5-990P15.1, Testis expressed 35, Testis specic conserved gene 24 kDa, TEX35, TSC24, Uncharacterized protein C1orf49.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf49 gene product has been provisionally designated C1orf49 pending further characterization. There are four isoforms of C1orf49 that are produced as a result of alternative splicing events.

Gene ID: 84066